Redefining Interventional Therapy for Severely Calcified Lesions

AVS is an early-stage medical device company that is focused on safely and effectively treating severely calcified arterial disease. AVS is the first company to develop the Pulse IVL™ System, a device that delivers intravascular lithotripsy therapy through a balloon-based platform. It is designed to be the only minimally invasive technology that gently shatters calcium and opens the artery using a single device.

Our Journey

  • 2017

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    • Company founded by clinical and engineering team from University of Michigan
    • Proof of concept developed

     

  • 2018

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    • Grant support received from NIH/Cleveland Clinic and U of M Fast Forward Medical Innovation

     

  • 2019

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    • Completion of successful animal study for safety
    • Performed early cadaver study with positive results
    • Patents filed with US Patents & Trademark Office

     

  • 2020

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    • Secured funding from visionary healthcare investment firm
    • Hired management team

     

  • 2021

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    • Built peripheral product
    • Completed cadaver studies with positive results confirmed by Renu Virmani
    • TCT Shark Tank Innovation finalist

     

  • 2022

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    • First patent granted
    • Successfully performed first in human cases
    • Initiated product development for coronary indication

     

  • 2023

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    • $28.8M Series B Round
    • PV FIH Complete and results presented at TCT
    • Relocated corporate office to Boston, MA seaport

     

 

 

CRF Shark Tank Logo

“We are proud to have been selected as a FINALIST in the CRF Shark Tank Innovation Competition”