AVS is redefining interventional therapy for severely calcified lesions with the PULSE IVL System and its novel, pulsatile mechanism of action that shatters calcium and expands the vessel, all with a single device.

Clinical Applications

Explore the First Application of the PULSE IVL System

Peripheral Artery Disease: Treating severely calcified lesions above the knee and in the femoropopliteal artery

The Next Frontier

Coronary Artery Disease

Peripheral Artery Disease
Coronary Artery Disease

Foundational Evidence

Promising preclinical results in severely calcified cadaveric limbs demonstrate ability to Pulse, Shatter and Expand without adjunctive devices

  • Intuitive, deliverable and technically feasible design
  • Shatters circumferential, eccentric, medial and intimal intravascular calcium
  • Expands the vessel using the same balloon that shatters the calcium


Foundation evidence
Post treatment demonstrates calcium shattering using PIVL


“The effects [of the PIVL™ System] are pretty striking and at least on parity with most of the other devices that have come across my desk.”    — Aloke Finn, MD, CV Path Institute