Mechanism of Action
With its novel Mechanism of Action (MOA) for fracturing arterial calcium, Pulse IVL™ empowers physicians to treat a wider range of patients faster, more efficiently, with fewer devices.
Not Your Standard MOA
While other IVL devices use electrical means of generating pressure peaks, Pulse IVL™ uses a differentiated mechanical MOA, converting pressurized CO2 to hydraulic pulsatile energy waves at a rate of 15/second. Once these waves reach the non-compliant balloon, they radiate uniformly and multi-directionally along the entire length of the balloon — fracturing intravascular calcium while expanding the vessel and maximizing luminal gain.
Lower profiles and better distal flexibility
No need for emitters
More efficient energy delivery
15 pulses/sec. vs. 1-2 pulses/sec
More uniform energy delivery
Energy delivered across the entire balloon vs. discrete electrode points/pulse
More uniform vessel expansion
MOA creates deep, multi-directional fractures vs. just longitudinal
Pulse IVL’s low crossing profile with flexible emitter-free shaft crosses lesions easily and is primed with saline to 1atm.
Pressurized CO2 impacts the proximal side of the diaphragm to generate hydraulic pressure waves that travel the length of the catheter shaft to the primed balloon.
- Fifteen pulses per second.
- Up to 5,000 pulses per case.
When the energy waves encounter the lesion, they create very short peak pressure pulses at 50atm that traverse the entire length of the balloon. This creates a continuous pulsatile force against the lesion until it fractures and yields.
The non-compliant balloon simultaneously post-dilates the lesion and expands the lumen.
Features of Our Unique MOA
Different
Uniform Waves Across Balloon
In our unique design, pressurized CO2 is used to create pulsatile hydraulic energy waves that travel down the catheter shaft to the balloon at 15 pulses/second. Peak pressure waves are created when these pulses reach the lesion, creating a change in fluid motion – fracturing the calcium and enabling the expansion of the vessel.
Deliverable
Reduced Need for Additional Devices
Designed without the need for electrical emitters, Pulse IVL™ can achieve much lower crossing profiles and distal flexibility — enabling physicians to effectively treat more challenging anatomy without additional devices.
Efficient
15 Pulses/Second
While other IVL systems only generate 1 to 2 pulses/second, Pulse IVL™ delivers 15 pulses/second, with a peak pressure wave of approximately 50atm, similar to other IVL modalities.
Easy to use
Compact Design and Universal Attachments
With its small console, IV pole attachment and standard Type E CO2 tank, the Pulse IVL™ system has a small footprint and does not require a large capital outlay. The console, handle and amplifier can be used across multiple indications.
The Pulse IVL™ System
Pulse IVL™ enables operators to treat patients with a wide range of arterial calcium disease faster, more efficiently, with fewer devices.
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