Founded in 2017, Amplitude Vascular Systems (AVS) is an early-stage medical device company that is focused on safely and effectively treating severely calcified arterial disease. AVS is the first company to develop Pulse Intravascular Lithotripsy™ (PIVL™), a therapy that is delivered through a balloon-based platform called the PULSE IVL™ System. It is designed to be the only minimally invasive technology that gently shatters calcium and opens the artery using a single device.

Upcoming Events

TCT 2023 MedTech Innovation Forum - -

Moscone Center San Francisco, CA TCT 2023 (

VIVA - Vascular Interventional Advances Forum - -

Investor Publications

We are committed to working with leading interventionalists to publish study data that supports the value of Pulse 
Intravascular Lithotripsy for the treatment of severely calcified vessels.